CLINICAL CASE OF RECURRENT ANGIOEDEMA IN A CHILD WITH LTP SYNDROME
DOI:
https://doi.org/10.32782/umv-2024.2.5Keywords:
LTP syndrome, allergen, angioedema, children, sensitization, oral allergy syndromeAbstract
The term “LTP syndrome” refers to a group of allergic reactions to allergens that are lipid-transport proteins (LTP). Plants containing LTP inhalation allergens are wormwood and plane tree, and products containing LTP are kiwi, strawberry, apple, apricot, orange, cherry, plum, raspberry. Cross-reactions may occur in individuals with LTP syndrome. LTP allergens are known as the main cause of IgE-mediated food allergy. Clinical manifestations of the syndrome can range from local manifestations (mild contact urticaria, oral allergy syndrome, or gastrointestinal problems) to anaphylaxis. Exercise, infections, nonsteroidal anti-inflammatory drugs, and dehydration can increase intestinal permeability and antigen absorption, thereby acting as cofactors in the development of allergic symptoms.
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