INFECTION RELATED TO MEDICAL CARE: MONITORING OF ANTIBIOTICS RESISTANCE AND ANTIBIOTICOTHERAPY
DOI:
https://doi.org/10.32471/umv.2709-6432.86.1067Keywords:
antibiotic resistance, Health care-associated infections, epidemiological monitoring, rational antibiotic therapy.Abstract
A search was conducted in the databases Scopus, Web of Science, MedLine, The Cochrane Library. Antibiotic resistance (ABR) is usually registered 1–3 years after the start of new drugs, especially in the hospital. Health care-associated infections (HCAIs) is absent upon admission to the hospital and occurs in the patient during treatment after 2 days after admission to the hospital, long-term care facility, outpatient clinic, and may occur after discharge from the hospital. HCAIs also includes occupational infections. There are three main strategies to combat the growing level of ABR: improving the infection control system, rational use of antibiotics, strengthening the safety of health care. The main purpose of epidemiological surveillance is to provide information to the relevant health authorities to develop appropriate measures to control the spread of ABR, optimization of antibacterial therapy in different categories of patients. With the help of WHONET program in each laboratory a computer database is created, which stores information about the patient (passport data), department, test material, date of receipt, the selected microorganism and its sensitivity to antimicrobial drugs. The program allows to cover all aspects of microbiological monitoring; correctly analyze the data obtained during testing of cultures isolated from patients in the hospital. It is important to use in the treatment of HCAIs optimal approaches to antibiotic therapy based on the use of pharmacokinetic / pharmacodynamic model.
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